Article
Utilising Automated Electrophysiological Platforms in Epilepsy Research.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Milligan Carol J, Pachernegg Svenja
Abstract excerpt
Genetic mutations have long been implicated in epilepsy, particularly in genes that encode ion channels and neurotransmitter receptors. Among some of those identified are voltage-gated sodium, potassium and calcium channels, and ligand-gated gamma-aminobutyric acid (GABA), neuronal nicotinic acetylcholine (CHRN), and glutamate receptors, making them key therapeutic targets. In this chapter we discuss the use of...
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