Article

Regulation of tmTNF-α Processing by FRMD8 in Triple-Negative Breast Cancer Metastasis: Insights into Molecular Pathway Dynamics

2024-09-27

Abstract excerpt

<h4>Purpose</h4> Breast cancer remains the leading cause of cancer-related mortality among women worldwide, with late-stage diagnoses prevalent in China resulting in significantly lower survival rates. This study focuses on identifying genes implicated in breast cancer metastasis, highlighting the role of Tumor Necrosis Factor-alpha (TNF-α) and its forms—transmembrane (tmTNF-α) and soluble (sTNF-α). <h4>Experimen...

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Literature Corpus work: 250b9949-8737-52e0-92c4-6087dc1a71dc
DOI: 10.1101/2024.09.26.615107

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