Article

Somatic genetic variants associated with aggressiveness of urothelial bladder cancer: a prospective cohort study

2025-05-12

Abstract excerpt

<title>Abstract</title> <p>Background Bladder cancer risk assessment using single nucleotide variants (SNVs) has focused on Caucasian and Chinese patients, with a significant gap in under-represented South Asian populations. This study examines the association of somatic SNVs with clinicopathological data in a Sri Lankan urothelial bladder cancer (UBC) cohort. Methods DNA was extracted from tumour specimens of...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 24dd88ce-b0cb-5286-ad03-8d855541b983
DOI: 10.21203/rs.3.rs-6553154/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Somatic genetic variants associated with aggressiveness of urothelial bladder cancer: a prospective cohort studyDOI 10.21203/rs.3.rs-6553154/v1Read

Genetic variability in 13q33 and 9q34 is linked to aggressiveness patterns and a higher risk of progression of non-muscle-invasive bladder cancer at the time of diagnosis.Semantic proximity Read

Clinical Exome Gene Panel Analysis of a Cohort of Urothelial Bladder Cancer Patients from Sri Lanka.Semantic proximity Read

Racial differences in genomic features and new trans-ancestry prognosis subtypes in bladder cancerSemantic proximity Read

Genetic variability in 8q24 confers susceptibility to urothelial carcinoma of the upper urinary tract and is linked with patterns of disease aggressiveness at diagnosis.Semantic proximity Read

Germline mutations in DNA repair genes are associated with bladder cancer risk and unfavourable prognosis.Semantic proximity Read

Somatic mutation profiles of muscle-invasive bladder cancer in Uganda: A cross-sectional study utilising whole-exome sequencingSemantic proximity Read

Targeted Deep Sequencing of Bladder Tumors Reveals Novel Associations between Cancer Gene Mutations and Mutational Signatures with Major Risk Factors.Semantic proximity Read

Genetic susceptibility to distinct bladder cancer subphenotypes.Semantic proximity Read

Comparative Genomic Landscape of Urothelial Carcinoma of the Bladder Among Patients of East and South Asian Genomic Ancestry.Semantic proximity Read

Mutational Landscape of Bladder Cancer in Mexican Patients: KMT2D Mutations and chr11q15.5 Amplifications Are Associated with Muscle Invasion.Semantic proximity Read

Integrated analysis of racial disparities in genomic architecture identifies a trans-ancestry prognostic subtype in bladder cancer.Semantic proximity Read

CTLA4 genetic variants associated with urothelial bladder cancer susceptibilitySemantic proximity Read