Article
Genetic susceptibility to distinct bladder cancer subphenotypes.
European urology - 1 Feb 2010
Guey Lin T, García-Closas Montserrat, Murta-Nascimento Cristiane, Lloreta Josep, Palencia Laia, Kogevinas Manolis, Rothman Nathaniel, Vellalta Gemma, Calle M Luz, Marenne Gaëlle, Tardón Adonina, Carrato Alfredo, García-Closas Reina, Serra Consol, Silverman Debra T, Chanock Stephen, Real Francisco X, Malats Núria
Abstract excerpt
BACKGROUND: Clinical, pathologic, and molecular evidence indicate that bladder cancer is heterogeneous with pathologic/molecular features that define distinct subphenotypes with different prognoses. It is conceivable that specific patterns of genetic susceptibility are associated with particular subphenotypes. OBJECTIVE: To examine evidence for the contribution of germline genetic variation to bladder cancer...
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