Article

Somatic mutation profiles of muscle-invasive bladder cancer in Uganda: A cross-sectional study utilising whole-exome sequencing

2025-09-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Muscle-invasive bladder cancer (MIBC) is a significant cause of cancer-related mortality in sub-Saharan Africa, yet its genomic landscape remains poorly characterised. In Uganda, nearly 60% of urothelial carcinoma cases are muscle-invasive (MIUC), with a near-equal sex distribution, in contrast to global trends. We aimed to define the somatic mutational landscape of Ugandan...

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Literature Corpus work: 6ba077e0-1080-5c70-b1eb-a0afd2695053
DOI: 10.1101/2025.09.15.25335787

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