Article
Genetic variability in 13q33 and 9q34 is linked to aggressiveness patterns and a higher risk of progression of non-muscle-invasive bladder cancer at the time of diagnosis.
BJU international - 1 Mar 2021
Lenfant Louis, Cancel-Tassin Geraldine, Gazut Stéphane, Compérat Eva, Rouprêt Morgan, Cussenot Olivier
Abstract excerpt
OBJECTIVE: To identify single nucleotide polymorphisms (SNPs) associated with patterns of aggressiveness of non-muscle-invasive bladder cancer (NMIBC). PATIENTS AND METHODS: From January 2011 to December 2018, 476 patients with NMIBC were prospectively included. The first step aimed to identify SNPs associated with aggressiveness patterns (e.g. ≥pT1or high-grade/Grade 3 or presence of carcinoma in situ) by...
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