Genetic variability in 8q24 confers susceptibility to urothelial carcinoma of the upper urinary tract and is linked with patterns of disease aggressiveness at diagnosis.

doi:10.1016/j.juro.2011.10.038

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Article

Genetic variability in 8q24 confers susceptibility to urothelial carcinoma of the upper urinary tract and is linked with patterns of disease aggressiveness at diagnosis.

The Journal of urology - 1 Feb 2012

Rouprêt Morgan, Drouin Sarah J, Cancel-Tassin Géraldine, Comperat Eva, Larré Stéphane, Cussenot Olivier

Abstract excerpt

PURPOSE: Upper urinary tract urothelial carcinoma is rare. Evidence shows that it behaves differently from urothelial bladder tumors. A polymorphism located at the T allele of rs9642880 on chromosome 8q24 is linked to an enhanced risk of bladder tumors. We explored the association of this polymorphism with susceptibility to upper urinary tract urothelial carcinoma. MATERIALS AND METHODS: We genotyped the...

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PMID: 22177160
DOI: 10.1016/j.juro.2011.10.038

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