Article

The coagulation factor IX (F9) loss of function prevents the cell cycle arrest induced by CDK4/6 inhibitors treatment

2021-11-30

Abstract excerpt

<h4>SUMMARY</h4> During this last decade the development of pro-senescence therapies has become an attractive strategy as cellular senescence acts as a barrier against tumour progression. In this context, CDK4/6 inhibitors induce senescence and have showed efficacy in reducing tumour growth in breast cancer patients. However, even though cancer cells are arrested after CDK4/6 inhibitor treatment, genes regulating...

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Literature Corpus work: 24d26298-15ec-58cd-9748-7c28ce42c30a
DOI: 10.1101/2021.11.30.470520

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