Article

MAESTRO uncovers tandem paralog dynamics as a core driver of fungal stress adaptation

2025-09-04

Abstract excerpt

<h4>SUMMARY</h4> Understanding how fungi adapt to diverse stresses is critical for mitigating emerging drug resistance and harnessing their robustness for biotechnology. Pichia kudriavzevii is a stress-tolerant and intrinsically drug-resistant yeast, with dual industrial and clinical importance. We analyzed 170 strains using MAESTRO, a machine-learning-assisted GWAS pipeline optimized for small cohorts. MAESTRO...

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Literature Corpus work: 249c7c06-8eb7-5d25-9e98-7ddc022cfd37
DOI: 10.1101/2025.08.29.673034

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