Article

Giant transposons promote strain heterogeneity in a major fungal pathogen

2024-06-28

Abstract excerpt

Fungal infections are difficult to prevent and treat in large part due to strain heterogeneity which confounds diagnostic predictability. Yet the genetic mechanisms driving strain-to-strain variation remain poorly understood. Here, we determined the extent to which Starships —giant transposons capable of mobilizing numerous fungal genes—generate genetic and phenotypic variability in the opportunistic human pathog...

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Literature Corpus work: 66bb2cb8-225f-5bc6-869a-6b830371b7e1
DOI: 10.1101/2024.06.28.601215

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