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The pangenome of <i>Aspergillus fumigatus</i> highlights the dynamics of gene gain-loss over evolutionary timescales in a human fungal pathogen

2026-04-16

Abstract excerpt

How fungal pathogens generate and maintain genetic diversity under sustained environmental drug pressure is central to understanding the emergence of antifungal resistance. In environmental moulds such as Aspergillus fumigatus , escalating exposure to agricultural fungicides that share targets with clinical azoles imposes chronic selection outside the host, yet the genomic mechanisms enabling long-term adaptation...

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Literature Corpus work
fa4edbfe-7b35-5fe9-80df-50799bc7f3bd
DOI
10.64898/2026.04.14.718449
Open publication

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The pangenome of <i>Aspergillus fumigatus</i> highlights the dynamics of gene gain-loss over evolutionary timescales in a human fungal pathogenDOI 10.64898/2026.04.14.718449
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