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Intra-tumoral genomic heterogeneity in rectal cancer: mutational status is dependent on preoperative biopsy depth and location.  

2020-10-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>Neoadjuvant therapy before surgical resection is indicated for patients with locally advanced rectal cancer. However, a significant number of patients show minimal or no response to neoadjuvant therapy. Unfortunately, we are currently unable to predict response and identify non-responding patients before neoadjuvant treatment is given. Genomic mutational status mi...

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Literature Corpus work
2483080c-52ba-5558-8b48-2d781a7ed8af
DOI
10.21203/rs.3.rs-20696/v3
Open publication

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Intra-tumoral genomic heterogeneity in rectal cancer: mutational status is dependent on preoperative biopsy depth and location.&nbsp;&nbsp;DOI 10.21203/rs.3.rs-20696/v3
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