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Deletion of Murine Gammaherpesvirus Gene <i>M2</i> in AID-Expressing B Cells Impairs Host Colonization and Viral Reactivation

2020-04-01

Abstract excerpt

<h4>ABSTRACT</h4> Gammaherpesviruses (GHVs) are DNA tumor viruses that establish life-long, chronic infections in lymphocytes of humans and other mammals. GHV infections are associated with numerous cancers, especially in immune compromised hosts. While it is known that GHVs utilize host germinal center (GC) B cell responses during latency establishment, an understanding of how viral gene products function in spe...

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Literature Corpus work
24512e2b-695f-5543-b55b-188d3e3e4688
DOI
10.1101/2020.03.30.016899
Open publication

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