Article

Regulation of ERK2 activity by dynamic <i>S</i> -acylation

2021-11-05

Abstract excerpt

The extracellular signal-regulated kinases (ERK1/2) are key effector proteins of the mitogen-activated protein kinase pathway, choreographing essential processes of cellular physiology. Critical in regulating these regulators are a patchwork of mechanisms, including post-translational modifications (PTMs) such as MEK-mediated phosphorylation. Here, we discover that ERK1/2 are subject to S -palmitoylation, a rever...

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Literature Corpus work: 23dfbc7e-3058-5201-b3c7-20ed7d573430
DOI: 10.1101/2021.11.05.467491

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