Article
Insulin-regulated protein palmitoylation impacts endothelial cell function.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2014
Wei Xiaochao, Song Haowei, Semenkovich Clay F
Abstract excerpt
OBJECTIVE: Defects in insulin signaling are associated with abnormal endothelial cell function, which occurs commonly in cardiovascular disease. Targets of insulin signaling in endothelial cells are incompletely understood. Protein S-palmitoylation, the reversible modification of proteins by the lipid palmitate, is a post-translational process relevant to cell signaling, but little is known about the role of...
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