Article
ACAD10 encodes two orphan enzymes in the ether lipid biosynthetic and salvage pathways
2025-09-13
Abstract excerpt
<h4>Summary</h4> Ether lipids play critical roles in membrane dynamics, antioxidant defense, and signaling. They comprise ∼20% of mammalian phospholipids, and disruptions in their metabolism cause severe genetic disorders and are associated with neurodegenerative and metabolic diseases. Ether lipids are synthesized de novo from glycolytic intermediates or salvaged from the diet. While the products of these pathw...
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Identifiers and source
- Literature Corpus work
- a30f1a77-189a-52a6-bdd2-dabe995ba05d
- DOI
- 10.1101/2025.09.10.675409