Article

OptoRheo: Simultaneous <i>in situ</i> micro-mechanical sensing and imaging of live 3D biological systems

2022-04-22

Abstract excerpt

Biomechanical cues from the extracellular matrix (ECM) are essential for directing many cellular processes, from normal development and repair, to disease progression. To better understand cell-matrix interactions, we have developed a new instrument named ‘OptoRheo’ that combines light sheet fluorescence microscopy with particle tracking microrheology. OptoRheo lets us image cells in 3D as they proliferate over se...

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Literature Corpus work: 23de9068-75d3-58e7-ae2b-a69d6d88a356
DOI: 10.1101/2022.04.21.489042

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