3D single-molecule super-resolution imaging of microfabricated multiscale fractal substrates for self-referenced cell imaging

Abstract excerpt

Microstructures arrayed over a substrate have shown increasing interest due to their ability to provide advanced 3D cellular models, which open new possibilities for cell culture, proliferation, and differentiation. Still, the mechanisms by which physical cues impact the cell phenotype are not fully understood, hence the necessity to interrogate cell behavior at the highest resolution. However, cell 3D high-resolu...

Topics

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• Cancer Cells and Metastasis
• Cell Image Analysis Techniques
• Coculture Techniques
• Ectoderm
• Imaging, Three-Dimensional
• Microscopy
• Phenotype
• Single-cell and spatial transcriptomics

Identifiers and source

Literature Corpus work

20cb9e59-e8aa-5194-a805-ba1ed08d5e80

DOI

10.1101/2023.11.07.566090