Article

Minocycline Promotes Functional Recovery in Ischemic Stroke by Modulating Microglia Polarization Through STAT1/STAT6 Pathways

2021-01-05

Abstract excerpt

<title>Abstract</title> <p>BackgroundIncreasing evidence suggests that microglia experience two distinct phenotypes after acute ischemic stroke (AIS): a deleterious M1 phenotype and a neuroprotective M2 phenotype. Promoting the phenotype shift of M1 microglia to M2 microglia is thought to improve functional recovery after AIS. Minocycline, a tetracycline antibiotic, can improve functional recovery after cerebral...

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Literature Corpus work: 23b85a06-5407-5864-b8fb-a79c35bc9564
DOI: 10.21203/rs.3.rs-138254/v1

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