Article
Treatment targets for M2 microglia polarization in ischemic stroke.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Sept 2018
Wang Ji, Xing Hongyi, Wan Lin, Jiang Xingjun, Wang Chen, Wu Yan
Abstract excerpt
As the first line of defense in the nervous system, resident microglia are the predominant immune cells in the brain. In diseases of the central nervous system such as stroke, Alzheimer's disease, and Parkinson's disease, they often cause inflammation or phagocytosis; however, some studies have found that despite the current controversy over M1, M2 polarization could be beneficial. Ischemic stroke is the third...
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