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An intermittent energy restriction diet ameliorates comorbid MASLD and T2DM through the <i>Klebsiella pneumoniae</i> /LPS/Hepatic HADHA-K353 acetylation axis

2026-07-13

Abstract excerpt

The intermittent energy restriction (iER) represents an effective dietary strategy for improving metabolic diseases including metabolic dysfunction-associated steatotic liver disease (MASLD) and type 2 diabetes mellitus (T2DM), yet the underlying mechanisms remain elusive. In this study, we integrated human clinical data, mouse models, and in vitro experiments to investigate the role of iER in modulating the gut-l...

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Literature Corpus work
23a61c25-7ea2-5fdb-bda1-ad98d6bcc38d
DOI
10.64898/2026.07.10.26357698
Open publication

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An intermittent energy restriction diet ameliorates comorbid MASLD and T2DM through the <i>Klebsiella pneumoniae</i> /LPS/Hepatic HADHA-K353 acetylation axisDOI 10.64898/2026.07.10.26357698
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