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Rfx3 controls outer hair cell differentiation, maintenance, and hair bundle formation by regulating the expression of <i>Insm1, Ikzf2</i> , and <i>Triobp</i> genes

2024-09-26

Abstract excerpt

The RFX family of transcription factors plays crucial roles in the regulation of ciliogenesis and organ development. Mutations of RFX transcription factors lead to various genetic diseases, including ciliopathies and hearing loss, although the underlying mechanisms remain unclear. This study comprehensively analyzed the expression patterns of RFX family members during different inner ear developmental stages. Rfx3...

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Literature Corpus work
23a23a32-ff97-54ac-99e1-1eeac03abdd4
DOI
10.1101/2024.09.24.614849
Open publication

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Rfx3 controls outer hair cell differentiation, maintenance, and hair bundle formation by regulating the expression of <i>Insm1, Ikzf2</i> , and <i>Triobp</i> genesDOI 10.1101/2024.09.24.614849
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