Article

Disruption of RFX family transcription factors causes autism, attention deficit/hyperactivity disorder, intellectual disability, and dysregulated behavior

2020-09-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> We describe a novel neurobehavioral syndrome of autism spectrum disorder, intellectual disability, and attention deficit/hyperactivity disorder associated with de novo or inherited deleterious variants in members of the RFX family of genes. RFX genes are evolutionarily conserved transcription factors that act as master regulators of central nervous system development and ciliogen...

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Literature Corpus work: 5f4b99d9-8a5d-5f62-b1ab-295c24f3f5f0
DOI: 10.1101/2020.09.09.20187104

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