Article
Identification and characterization of novel human tissue-specific RFX transcription factors
1 Aug 2008
Abstract excerpt
BACKGROUND: Five regulatory factor X (RFX) transcription factors (TFs)-RFX1-5-have been previously characterized in the human genome, which have been demonstrated to be critical for development and are associated with an expanding list of serious human disease conditions including major histocompatibility (MHC) class II deficiency and ciliaophathies. RESULTS: In this study, we have identified two additional RFX...