Article

Composition and structure of stratum corneum intercellular lipids in patients with osimertinib-induced hand-foot syndrome

2026-03-24

Abstract excerpt

<title>Abstract</title> <p> <bold>Purpose:</bold> Osimertinib (OSM), a third-generation epidermal growth factor receptor tyrosine kinase, causes skin disorders, such as hand-foot syndrome (HFS), which impairs skin barrier function. Stratum corneum (SC) lipids play an important role in skin barrier function. This study aimed to compare the SC lipid composition and structure of healthy participants with those of...

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Literature Corpus work: 239c0c8f-274d-56d2-b12d-4b68bbc1fe45
DOI: 10.21203/rs.3.rs-9156086/v1

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