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Unraveling Barrier Properties of Three Different In-House Human Skin Equivalents

9 Sept 2011

Abstract excerpt

Human skin equivalents (HSEs) are three-dimensional culture models that are used as a model for native human skin. In this study the barrier properties of two novel HSEs, the fibroblast-derived matrix model (FDM) and the Leiden epidermal model (LEM), were compared with the full-thickness collagen model (FTM) and human skin. Since the main skin barrier is located in the lipid regions of the upper layer of the...

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PMID: 21902617
DOI: 10.1089/ten.tec.2011.0175

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