Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human skin equivalents: Impaired barrier function in relation to the lipid and protein properties of the stratum corneum

18 May 2021

Abstract excerpt

To advance drug development representative reliable skin models are indispensable. Animal skin as test model for human skin delivery is restricted as their properties greatly differ from human skin. In vitro 3D-human skin equivalents (HSEs) are valuable tools as they recapitulate important aspects of the human skin. However, HSEs still lack the full barrier functionality as observed in native human skin,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advancements in Transdermal Drug Delivery
Share to Dermatology and Skin Diseases
Share to Skin Protection and Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34015420
DOI: 10.1016/j.addr.2021.05.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human skin equivalents: Impaired barrier function in relation to the lipid and protein properties of the stratum corneumPMID 34015420Read ↗

Unraveling Barrier Properties of Three Different In-House Human Skin EquivalentsSemantic proximity Read ↗

Barrier Properties of an N/TERT-Based Human Skin EquivalentSemantic proximity Read ↗

Modelling the Complexity of Human Skin In VitroSemantic proximity Read ↗

Improved epidermal barrier formation in human skin models by chitosan modulated dermal matricesSemantic proximity Read ↗

Barrier Functions of Human Skin: A Holistic ViewSemantic proximity Read ↗

An <i>ex vivo human</i> skin model for studying skin barrier repairSemantic proximity Read ↗

The relationship between skin function, barrier properties, and body‐dependent factorsSemantic proximity Read ↗

Nature versus nurture: does human skin maintain its stratum corneum lipid properties <i>in vitro</i>?Semantic proximity Read ↗

Skin equivalents: skin from reconstructions as models to study skin development and diseasesSemantic proximity Read ↗

Skin microbiota and human 3D skin modelsSemantic proximity Read ↗

Human skin equivalents cultured under hypoxia display enhanced epidermal morphogenesis and lipid barrier formationSemantic proximity Read ↗

Knock-down of filaggrin does not affect lipid organization and composition in stratum corneum of reconstructed human skin equivalents.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.