Article
The role of fatty acid elongation in epidermal structure and function
1 Apr 2011
Abstract excerpt
Heterogeneous molecular species of epidermal ceramide (Cer) play critical roles in forming a competent permeability barrier of lamellar membrane structures in the stratum corneum, which is a prerequisite to preventing excess water loss for terrestrial mammals. Lipids containing very long chain lengths of fatty acids (VLCFA) (hydrocarbon chain lengths over 28) have been found in selected tissues, including...
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