Article

Normative Modelling of Brain Volume for Diagnostic and Prognostic Stratification in Multiple Sclerosis

2025-09-15

Abstract excerpt

<h4>Background</h4> Brain atrophy is a hallmark of multiple sclerosis (MS). For clinical translatability and individual-level predictions, brain atrophy needs to be put into context of the broader population, using reference or normative models. <h4>Methods</h4> Reference models of MRI-derived regional brain volumes were established from a large healthy control (HC) multi-cohort dataset (N=63 115, 51% females)....

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Literature Corpus work: 237fe012-f1fd-5dfa-a8f3-2b32b9fd1aee
DOI: 10.1101/2025.09.14.25335702

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