Article

The Role of Network Connectivity and Transcriptomic Vulnerability in Shaping Grey Matter Atrophy in Multiple Sclerosis

2026-02-16

Abstract excerpt

Clinical progression is strongly linked to grey matter atrophy in multiple sclerosis (MS), detectable early on MRI and progressing non-randomly across the brain. However, the mechanisms driving its spatio-temporal progression and individual variability remain unclear. Using MRIs from 2,187 participants, alongside normative data, we systematically investigated network-based mechanisms underlying MS-related atrophy....

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Literature Corpus work: 20a1d7a5-e138-58cb-83de-65f864617f4b
DOI: 10.64898/2026.02.13.26346243

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