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Lifespan Modeling of Choroid Plexus Volume in Multiple Sclerosis and Its Dynamic Associations With Clinical, MRI, and HLA Susceptibility.

Neurology(R) neuroimmunology & neuroinflammation - 1 Jul 2026

Preziosa Paolo, Corazzolla Gianluca, Meani Alessandro, Margoni Monica, Storelli Loredana, Pagani Elisabetta, Rubin Martina, Clarelli Ferdinando, Mascia Elisabetta, Sorosina Melissa, Esposito Federica, Filippi Massimo, Rocca Maria A

Abstract excerpt

BACKGROUND AND OBJECTIVES: The choroid plexus (ChP) regulates CSF production and CNS homeostasis. In multiple sclerosis (MS), ChP enlargement occurs early in the disease course, yet its normative lifespan trajectory and relationship with MS-specific features remain poorly defined. We aimed to define the normative ChP volume model, to characterize its trajectory across the healthy lifespan, and to assess ChP...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 42228891
DOI: 10.1212/NXI.0000000000200593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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