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Article

Progression of regional atrophy in the left hemisphere contributes to clinical and cognitive deterioration in multiple sclerosis: A 5-year study.

Human brain mapping - 1 Nov 2017

Preziosa Paolo, Pagani Elisabetta, Mesaros Sarlota, Riccitelli Gianna C, Dackovic Jelena, Drulovic Jelena, Filippi Massimo, Rocca Maria A

Abstract excerpt

In this longitudinal study, we investigated the regional patterns of focal lesions accumulation, and gray (GM) and white matter (WM) atrophy progression over a five-year follow-up (FU) in multiple sclerosis (MS) patients and their association with clinical and cognitive deterioration. Neurological, neuropsychological and brain MRI (dual-echo and 3D T1-weighted sequences) assessments were prospectively performed...

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Identifiers

PMID: 28792103
DOI: 10.1002/hbm.23755
PMCID: PMC6866796

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