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Pathway-enhanced Transformer-based robust model for quantifying cell types of origin of cell-free transcriptome

2024-02-28

Abstract excerpt

Analyzing cell types of origin of cell-free RNA can enhance the resolution of liquid biopsies, thereby deepening the understanding of molecular and cellular changes in development and disease processes. Existing deconvolution methods typically rely on meticulously curated gene expression profiles or employ deep neural network with vast and complex solution spaces that are difficult to interpret. These approaches o...

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Literature Corpus work
2372d6b1-0014-5a84-bef9-6212ad0d625a
DOI
10.1101/2024.02.28.582494
Open publication

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Pathway-enhanced Transformer-based robust model for quantifying cell types of origin of cell-free transcriptomeDOI 10.1101/2024.02.28.582494
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