Article

Multi‑algorithm deconvolution and entropy‑based tracing identify maternal‑fetal transcriptional drivers of preeclampsia

2026-06-10

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Preeclampsia (PE) is a multifactorial pregnancy disorder with early molecular origins. Numerous transcriptomic datasets (RNA‑seq and microarray) have been generated from placental tissues, but they represent mixed signals from both maternal and fetal cells. Single‑cell RNA‑seq can resolve cellular origins, yet it is often limited by sample size and clinical av...

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Literature Corpus work: fea3d772-7d29-5897-8b65-8e295e5c09f1
DOI: 10.21203/rs.3.rs-9975927/v1

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