Article

A novel method to enhance the sensitivity of marker detection using a refined hierarchical prior of tissue similarities

2015-06-11

Abstract excerpt

<h4>Motivation</h4> Identification of biochemical processes that drive the transformation of a totipotent cell into various cell types is essential to our understanding of living systems. This complex machinery determines how tissues differ in terms of their anatomy, physiology, morphology, and, more importantly, how various cellular control mechanisms contribute to the observed similarities/ differences. Tissue-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c774b24e-54a2-580b-af85-cd91a3cb26e4
DOI: 10.1101/020685

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A novel method to enhance the sensitivity of marker detection using a refined hierarchical prior of tissue similaritiesDOI 10.1101/020685Read

Robust and Rigorous Identification of Tissue-Specific Genes by Statistically Extending Tau ScoreSemantic proximity Read

Enhancement of Network Architecture Alignment in Comparative Single-Cell StudiesSemantic proximity Read

Tissue-Specific Enrichment Analysis (TSEA) to decode tissue specificitySemantic proximity Read

Graph Fourier transform for spatial omics representation and analyses of complex organsSemantic proximity Read

Prioritizing and characterizing functionally relevant genes across human tissuesSemantic proximity Read

Spatial Deconvolution of Cell Types and Cell States at Scale Utilizing TACITSemantic proximity Read

A limited set of transcriptional programs define major cell typesSemantic proximity Read

The Gene Expression Landscape of Disease GenesSemantic proximity Read

Spatial omics representation and functional tissue module inference using graph Fourier transformSemantic proximity Read

High order expression dependencies finely resolve cryptic states and subtypes in single cell dataSemantic proximity Read

Semi-automated annotation refinement accelerates cell type identification in brain spatial and single-cell studiesSemantic proximity Read

Spatial Deconvolution of Cell Types and Cell States at Scale Utilizing TACITSemantic proximity Read