Article

WAD: a wavelet-based linear programming method using L1-minimal reconstruction loss for accessible chromatin data deconvolution

2025-12-01

Abstract excerpt

Bulk tissue-based accessible chromatin studies provide summary annotations across all cell types within the tissue. These annotations can be skewed by varying proportions of individual cell types, especially in the context of disease studies. Estimated sample specific cell-type proportions can be used to mitigate effects of this variability while also addressing whether there exist significant alterations in cell...

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Literature Corpus work: 111791e9-67ab-54b9-a9e7-d85d239d4f17
DOI: 10.1101/2025.11.26.690776

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