Article

Lower expression of the RASSF10 gene induces myeloma cell proliferation due to hypermethylation of the gene promoter in multiple myeloma

2020-06-29

Abstract excerpt

<title>Abstract</title> <bold>Background:</bold> Multiple myeloma (MM) is an incurable malignant neoplasm of plasma cells, in which genetic defects, epigenetic aberrations and bone marrow microenvironment are involved in the pathogenesis. <italic>RASSF10</italic> acts as a tumor suppressor gene by methylation in glioma and several other cancers, but its role in MM remains unknown. <bold>Methods: </bold>In orde...

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Literature Corpus work: 23578f16-5617-5143-b9ea-6e0c1b9e883c
DOI: 10.21203/rs.3.rs-23701/v2

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