Aberrant micro<scp>RNA</scp> expression in multiple myeloma

Abstract excerpt

Multiple myeloma (MM) is a devastating disease with a complex biology, and in spite of improved survivability by novel treatment strategies over the last decade, MM is still incurable by current therapy. MicroRNAs (miRNAs) are small, non-coding RNA molecules that regulate gene expression at a post-transcriptional level. More than half of all protein coding genes are estimated to be controlled by miRNAs, and their...

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