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Article

MicroRNAs: Novel Crossroads between Myeloma Cells and the Bone Marrow Microenvironment

1 Jan 2016

Abstract excerpt

Multiple myeloma (MM) is a hematologic malignancy of differentiated plasma cells that accumulate in the bone marrow, where a complex microenvironment made by different cell types supports proliferation, survival, and drug resistance of tumor cells. MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression at posttranscriptional level. Emerging evidence indicates that miRNAs are aberrantly...

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PMID: 26881223
DOI: 10.1155/2016/6504593

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