Article

Significance of a Tumor Microenvironment-Mediated P65-miR-30a-5p-BCL2L11 Amplification Loop in Multiple Myeloma

2021-09-17

Abstract excerpt

<title>Abstract</title> <p>Despite significant progress in the treatment of myeloma, multiple myeloma (MM) remains an incurable hematological malignancy due to cell adhesion-mediated drug resistance (CAM-DR) phenotype. However, data on the molecular mechanisms underlying the CAM-DR remains scanty. Here, we identified a miRNA-mRNA regulatory network in myeloma cells that are directly adherent to bone marrow stroma...

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Literature Corpus work: e076b079-397a-5438-9a24-dc2075b1578f
DOI: 10.21203/rs.3.rs-880497/v1

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