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Article

Role of epigenetics-microRNA axis in drug resistance of multiple myeloma

17 Jun 2017

Abstract excerpt

Despite administration of novel therapies, multiple myeloma (MM) remains incurable with resistance to drugs leading to relapse in most patients. Thus, it is critical to understand the detailed mechanisms underlying the drug resistance of MM and develop more effective therapeutic strategies. Genetic abnormalities are well known to play a central role in MM pathogenesis and therapy resistance; however, epigenetic...

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PMID: 28623912
DOI: 10.1186/s13045-017-0492-1

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