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<i>Ex-vivo</i> mouse precision cut tumour slices for modelling hepatocellular carcinoma; A 3Rs solution for at-scale drug screening

2024-09-18

Abstract excerpt

Disease modelling is vital for improving knowledge of disease mechanisms and for development of new therapeutic molecules and strategies. Modelling the intact living tumour microenvironment (TME) is increasingly considered to be vital not only for gaining a better understanding of the biology of cancer but for examining the efficacy of novel oncology drugs. To date, pre-clinical mouse models of cancer have represe...

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Literature Corpus work
233bd1a9-cac6-5fb9-9093-242fd0316502
DOI
10.1101/2024.09.16.613213
Open publication

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<i>Ex-vivo</i> mouse precision cut tumour slices for modelling hepatocellular carcinoma; A 3Rs solution for at-scale drug screeningDOI 10.1101/2024.09.16.613213
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