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Article

Experimental mouse models for hepatocellular carcinoma research

20 Jul 2009

Abstract excerpt

Every year almost 500,000 new patients are diagnosed with hepatocellular carcinoma (HCC), a primary malignancy of the liver that is associated with a poor prognosis. Numerous experimental models have been developed to define the pathogenesis of HCC and to test novel drug candidates. This review analyses several mouse models useful for HCC research and points out their advantages and weaknesses. Chemically induced...

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Identifiers

PMID: 19659896
DOI: 10.1111/j.1365-2613.2009.00656.x

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