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DNA methylation-based epigenetic signatures predict somatic genomic alterations in gliomas

29 Jul 2022

Abstract excerpt

Molecular classification has improved diagnosis and treatment for patients with malignant gliomas. However, classification has relied on individual assays that are both costly and slow, leading to frequent delays in treatment. Here, we propose the use of DNA methylation, as an emerging clinical diagnostic platform, to classify gliomas based on major genomic alterations and provide insight into subtype...

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PMID: 35906213
DOI: 10.1038/s41467-022-31827-x

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