Article

TEX43, a Testis-Enriched Microtubule-Associated Gene, Exerts Minimal Impact on Spermatogenesis and Fertility in Mice and Humans

2025-12-05

Abstract excerpt

<title>Abstract</title> <p>Purpose Testis-specific TEX family genes are critical for spermatogenesis, but TEX43’s function remains uncharacterized. This study aimed to delineate TEX43’s role in spermatogenesis and fertility using murine models and clinical data. Methods Tex43 expression was analyzed via quantitative reverse transcription-polymerase chain reaction (Q-PCR), immunohistochemistry (IHC), and western b...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 22cc423f-bf5e-5c68-8414-3c0aec743428
DOI: 10.21203/rs.3.rs-8181104/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

TEX43, a Testis-Enriched Microtubule-Associated Gene, Exerts Minimal Impact on Spermatogenesis and Fertility in Mice and HumansDOI 10.21203/rs.3.rs-8181104/v1Read

Loss-of-function variant in TEX44 cause male infertility with asthenoteratozoospermia in humans and miceSemantic proximity Read

From Spermatogenesis to Sperm Function: Bioinformatics and Experimental Insights into the Role of TEKT Genes in Sperm FateSemantic proximity Read

Bi-allelic human TEKT3 mutations cause male infertility with oligoasthenoteratozoospermia owing to acrosomal hypoplasia and reduced progressive motility.Semantic proximity Read

Exome sequencing reveals a nonsense mutation in TEX15 causing spermatogenic failure in a Turkish family.Semantic proximity Read

Scrutinizing the human TEX genes in the context of human male infertilitySemantic proximity Read

Disruption of TEX38 impairs sperm morphogenesis and the migration of sperm into the oviductSemantic proximity Read

Genomic study of TEX15 variants: prevalence and allelic heterogeneity in men with spermatogenic failureSemantic proximity Read

Human testis-expressed (TEX) genes: a review focused on spermatogenesis and male fertilitySemantic proximity Read

TENT5D disruption causes oligoasthenoteratozoospermia and male infertility.Semantic proximity Read

The mammalian-specific Tex19.1 gene plays an essential role in spermatogenesis and placenta-supported development.Semantic proximity Read

The lack of Tex44 causes severe subfertility with flagellar abnormalities in male miceSemantic proximity Read

The human testis-specific proteome defined by transcriptomics and antibody-based profilingSemantic proximity Read