Article
The mammalian-specific Tex19.1 gene plays an essential role in spermatogenesis and placenta-supported development.
Human reproduction (Oxford, England) - 1 Aug 2013
Tarabay Yara, Kieffer Emmanuelle, Teletin Marius, Celebi Catherine, Van Montfoort Aafke, Zamudio Natasha, Achour Mayada, El Ramy Rosy, Gazdag Emese, Tropel Philippe, Mark Manuel, Bourc'his Déborah, Viville Stéphane
Abstract excerpt
STUDY QUESTION: What is the consequence of Tex19.1 gene deletion in mice? SUMMARY ANSWER: The Tex19.1 gene is important in spermatogenesis and placenta-supported development. WHAT IS KNOWN ALREADY: Tex19.1 is expressed in embryonic stem (ES) cells, primordial germ cells (PGCs), placenta and adult gonads. Its invalidation in mice leads to a variable impairment in spermatogenesis and reduction of perinatal...
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