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The lack of Tex44 causes severe subfertility with flagellar abnormalities in male mice

15 May 2024

Abstract excerpt

By analyzing a mouse Interspecific Recombinant Congenic Strain (IRCS), we previously identified a quantitative trait locus (QTL), called Mafq1 on mouse chromosome 1, that is associated with male hypofertility and ultrastructural sperm abnormalities. Within this locus, we identified a new candidate gene that could be implicated in a reproductive phenotype: Tex44 (Testis-expressed protein 44). We thus performed a...

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PMID: 38750428
DOI: 10.1186/s11658-024-00587-5

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