Article
Prenatal ethanol exposure impairs hippocampal plasticity and cognition in adolescent mice
22 Oct 2024
Abstract excerpt
BACKGROUND: Prenatal alcohol exposure (PAE) induces a wide range of neurodevelopmental disabilities that are grouped under the term 'fetal alcohol spectrum disorders' (FASD). The effects of PAE on brain development are dependent on complex neurochemical events, including modification of AMPA receptors (AMPARs). We have recently found that chronic ethanol (EtOH) exposure decreases AMPA-mediated neurotransmission...
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