Article

Receptor‐Targeted Drug Delivery and the (Many) Problems We Know of: The Case of CD44 and Hyaluronic Acid

2018-04-16

Abstract excerpt

Abstract CD44 is best known for being the most common receptor of hyaluronic acid (HA). It is also a heterogeneous molecule: while its standard isoform (CD44s) is ubiquitously expressed, there are also a range of variants (CD44v), and both CD44s and CD44v undergo a variety of post‐translational modifications. The signaling roles and frequent overexpression of both CD44s and CD44v in cancer (e.g., in cancer initiat...

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Literature Corpus work: 229e805e-9c3a-57e7-9a82-fd316d0c7b90
DOI: 10.1002/adbi.201800049

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