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Article

CD147: regulator of hyaluronan signaling in invasiveness and chemoresistance.

Advances in cancer research - 1 Jan 2014

Grass G Daniel, Dai Lu, Qin Zhiqiang, Parsons Chris, Toole Bryan P

Abstract excerpt

Major determinants that influence negative outcome in cancer patients are the abilities of cancer cells to resist current therapies and to invade surrounding host tissue, consequently leading to local and metastatic dissemination. Hyaluronan (HA), a prominent constituent of the tumor microenvironment, not only provides structural support but also interacts with cell surface receptors, especially CD44, that...

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PMID: 25081536
DOI: 10.1016/B978-0-12-800092-2.00013-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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